-- Creative Proteomics today announced the launch of its advanced Plant Untargeted Metabolomics service, a specialized offering designed to provide researchers with comprehensive, high-resolution profiling of the plant metabolome. The service directly addresses the inherent analytical challenges of plant systems, characterized by immense chemical diversity and a wide dynamic range of metabolite concentrations.
This new service moves beyond conventional metabolite profiling by integrating a multi-platform strategy centered on state-of-the-art Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) systems. Recognizing that no single analytical method can capture the entirety of the plant metabolome—estimated to exceed 200,000 unique molecules—Creative Proteomics employs a suite of high-performance instruments, including Thermo Fisher Orbitrap Exploris™ and Q Exactive™ series mass spectrometers for high-resolution accurate mass (HRAM) detection, and AB Sciex QTRAP® systems for high-sensitivity quantification. This approach ensures robust coverage of diverse chemical classes, from polar primary metabolites to nonpolar lipids and specialized secondary metabolites.
"The challenge in plant metabolomics isn't just detection; it's achieving comprehensive coverage and meaningful biological interpretation," stated the Head of Metabolomics at Creative Proteomics. "A plant's metabolic state is a dynamic footprint of its genotype and its interaction with the environment. Our platform is engineered to capture that footprint with exceptional detail. By optimizing extraction protocols for different tissues and leveraging multiple chromatographic separations and mass spectrometry modes, we minimize analytical bias and deliver a dataset of superior depth and quality."
A key component of the service is its sophisticated bioinformatics pipeline. Following data acquisition, the raw data undergoes rigorous processing, including peak deconvolution, alignment, and normalization. The service then provides advanced statistical analysis, including multivariate pattern recognition methods such as Principal Component Analysis (PCA) and Orthogonal Partial Least Squares-Discriminant Analysis (OPLS-DA), to identify statistically significant metabolic alterations between experimental groups. Subsequent metabolite identification is performed against extensive libraries, and pathway analysis tools like KEGG are utilized to place these changes into a biological context.
The service is tailored for a range of advanced research applications, including:
- Functional Genomics: Elucidating gene function by characterizing the metabolic phenotype of mutants or transgenic lines.
- Crop Science: Identifying metabolic quantitative trait loci (mQTLs) and biomarkers for stress resistance, yield, and nutritional value.
- Plant-Microbe Interactions: Mapping the metabolic crosstalk between plants and pathogens or symbionts.
- Natural Product Discovery: Systematically screening plant extracts for novel bioactive compounds.
With this technically advanced service, Creative Proteomics provides the global plant science community with a powerful tool to generate novel hypotheses, validate genomic data, and accelerate the pace of discovery.
About Creative Proteomics
Creative Proteomics is a specialist contract research organization (CRO) providing robust services in proteomics, metabolomics, and bioinformatics. Through a commitment to cutting-edge technology and scientific rigor, the company empowers academic, pharmaceutical, and agricultural research worldwide.
Contact Info:
Name: Melissa George
Email: Send Email
Organization: Creative Proteomics
Website: https://www.creative-proteomics.com/
Release ID: 89166130
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