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From Bench to Breakthrough: Creative Biolabs Accelerates Immune-Based Discoveries
Due to the ever-increasing number of requests for precision tools used in immunotherapy research, Creative Biolabs has responded by launching a suite of advanced product options to support and strengthen the development of next-generation immune-based therapies. Hemolysis Assay for Solutes: A New Benchmark for Complement Activation Study Complement activation is a key safety and efficacy process for therapeutic agents, in particular, unwanted immune responses associated with monoclonal antibodies, liposomes, and nanoparticles. Creative Biolabs' hemolysis assay for solutes demonstrates a versatile and cost-effective preclinical 2×96-well high-throughput format hemolysis assay for assessing complement-mediated hemolysis across multiple species. It is an excellent option for screening solutes that trigger unwanted immune responses, providing hematology researchers with reliable hemolysis data to pursue formulating and dosing adjustments. Double Emulsion Droplet Chip: Microfluidics for Precision Encapsulation Microfluidic technologies are changing how scientists are able to manipulate cells, reagents, and biomolecules at the microscale. The double emulsion droplet chip from Creative Biolabs uses a flow-focusing design and localized surface modifications to create double emulsion droplets with a very uniform structure. "The chip is made from glass for durability, and it is also able to function at high pressure and at high temperatures, allowing it to be used to encapsulate immune cells, build microreactors, and facilitate single-cell assays. The chip nozzle sizes can be customized; it also works with many surfactants." So researchers can use this technology to offer control and reproducibility that enables the investigation of novel drug delivery models, synthetic biology systems, and cell-based assays. Human Alveolar Macrophages: A Physiology-Relevant Model of Innate Immunity Understanding how macrophages participate in immune regulation, inflammation, and tissue homeostasis is a crucial aspect of developing effective immunotherapies. So, they now offer isolated human alveolar macrophages . These cells are isolated from the lungs of healthy donors and pathogen-tested. "Researchers are paying more and more attention to human alveolar macrophages in developing new treatments. They're being used in things like drug delivery and immune system therapies, which could really help fight serious lung infections and boost overall lung health," said a scientist. Driving Innovation in Immunotherapy Research The new product line reflects their commitment to empowering researchers using scientifically independent, human-relevant, and engineered solutions, which will enable researchers to develop therapeutics faster, safer, and more effectively. For detailed product and custom services information, visit https://www.creative-biolabs.com/complement-therapeutics/. About Creative Biolabs Creative Biolabs is dedicated to improving immunotherapy research and exploring innovative technologies to enable deeper discovery, greater experimental precision, and increased speed-to-discovery for the immune sciences.
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- August 25, 2025Science
Creative Biolabs Drug Discovery Models: From 3D Tumor Spheroids to "Miniaturized Human Bodies" on a Chip
In the pursuit of new drugs and disease research, scientists are continuously pushing beyond the limitations of traditional cell assays and animal models, instead using innovative systems that more closely reflect human physiological states. 3D Tumor Spheroids : Restoring the Authenticity of the Microenvironment Conventional two-dimensional cell culturing remains ubiquitous for its ease, yet it fails to represent the intricate cell interactions in a three-dimensional context. In response, Creative Biolabs provides custom-engineered 3D tumor spheroid model services. These models more closely resemble the migration, proliferation, and treatment resistance of cancer cells by simulating the spatial structure and nutritional gradients of tumors in vitro . "If 2D cultures show us a 'single building,' then spheroid models reveal a 'miniature city,'" as one scientist at Creative Biolabs vividly explained. The expert team at Creative Biolabs has already applied different types of spheroid models to drug screening, target validation, and mechanism studies, helping researchers more accurately assess the potential of drug candidates in the preclinical stage. Creative Biolabs offers various constructed tumor spheroids, thereby catering to clients' specific requirements. * 3D Human Blood-Brain Barrier Spheroid Model * 3D Human Retinal Pigment Epithelial Spheroid Model * 3D Human Cortical Spheroid Model * 3D Hepatocyte-Stellate Cell Spheroid Model "Miniaturized Human Bodies" on a Chip If 3D spheroids represent the "micro-ecosystem" of tumor research, then Organ-on-a-Chip is the " in vitro human body" of drug development. In order to replicate the structure and capabilities of actual human organs, Creative Biolabs is extending its offerings in this field by using microfluidic technology to embed cells and tissues within chip platforms. The Disease-on-a-Chip model platforms developed by Creative Biolabs have already become indispensable tools for pharmaceutical companies to evaluate drug efficacy and safety. Among the various models * Lung-on-a-Chip can reconstruct gas exchange and airway inflammation. * Liver-on-a-Chip recreates metabolic activity and drug responses. * Gut-on-a-Chip reveals the dynamic interplay between microbes and host immunity. * Heart-Liver-Skin Three-Organ-on-a-Chip enables simultaneous observation of cardiac, hepatic, and skin responses in a connected microfluidic system. Chip-based systems exhibit great promise, particularly in medication safety evaluation and personalized medicine research, as they can produce more predictive outcomes faster than traditional animal models. As a result, more and more partners are choosing Creative Biolabs to integrate these models into their development pipelines, thereby improving efficiency and reducing the risk of failure. Organ-on-a-Chip and 3D spheroids are complementary tools rather than substitutes for one another. They are developing a multifaceted, multilayered research platform that offers preclinical studies more trustworthy evidence. The scientist summarized it well: "Drug discovery is moving toward greater precision and personalization. What we are doing is helping researchers bring laboratory experiments closer to the reality of human biology." For more cutting-edge solutions, visit https://www.creative-biolabs.com/3d-biology/. About Creative Biolabs Whether through customized 3D tumor spheroid models or comprehensive multi-organ chip platforms, Creative Biolabs delivers professional support to research teams worldwide.
- August 21, 2025Science
Creative Biolabs Initiates Complement Testing Solutions and Microfluidic Platforms
Creative Biolabs, the global leader in immunological assay development and microfluidic technology, is delighted to announce the expansion of its complement system testing portfolio by launching enhanced C1q binding test and C3b deposition assay services, as well as cutting-edge microfluidic platforms. The strategic integration offers unparalleled sensitivity, throughput, and custom-made solutions for researchers involved in immunotherapy, vaccine development, and autoimmune disease research. Creative Biolabs' complement C1q binding assay enables scientists to determine the complement activation potential of biologics, including monoclonal antibodies, Fc-fusion proteins, and antigen-antibody complexes. Being the classical complement pathway initiator, C1q is the key player in immune surveillance. Its binding activity needs to be characterized in order to predict complement-dependent cytotoxicity (CDC) and therapeutic safety profiles. They provide both ELISA-format and surface plasmon resonance (SPR) formats, which allow customers to choose between high-throughput screening or real-time kinetic profiling. With the provision of flexible ligand orientation, species customization, and the capacity for pairing with downstream complement assays (e.g., C3b, C4b, C5b-9), the service is tailored to suit a range of research needs. To augment the C1q assay, the C3b deposition assay quantitates the deposition of C3b on cell surfaces—a central event in amplifying the complement cascade. The assay is important in determining drug efficacy, dissecting disease mechanisms, and profiling immune evasion strategies. The simplified workflow of Creative Biolabs includes sample preparation, controlled complement activation, high-sensitivity detection by ELISA or flow cytometry, and professional data analysis. The clients receive comprehensive reports with quantitative data and statistical analysis, ensuring reproducibility and clarity. What makes Creative Biolabs an equally powerful partner in this field is its profound experience and proprietary technology in the field of microfluidics. Scientists can leverage Creative Biolabs' advanced lab-on-a-chip platforms for integrating sample handling, reaction control, and detection—all within miniature, customizable devices. Such microfluidic systems minimize reagent use and enable high-throughput analysis of numerous samples, significantly accelerating research without sacrificing analytical precision. By integrating immunological expertise with microfluidic engineering, Creative Biolabs allows scientists to develop deeper insights into complement biology more quickly and accurately. Whether you're developing next-generation biologics or investigating immune dysregulation, this integrated platform offers a scalable, customized solution that responds to the demands of modern biomedical research. For more information, please visit https://www.creative-biolabs.com/complement-therapeutics/. About Creative Biolabs Creative Biolabs is a global leading custom service biotechnology company, specialized in antibody engineering, immunoassay development, and microfluidics technology. From complement therapeutics to organ-on-a-chip, the company is committed to advancing science through precision, flexibility, and collaboration.
- August 14, 2025Science
Government Lab Enterprises Adds Ultra-Low Temperature Chest Freezer to Equipment Offerings
Government Lab Enterprises, a provider of durable, compliant, and adaptable laboratory furniture and equipment, has added the Arctiko SF150 -30°C to -60°C Chest Freezer to its equipment lineup. The 4.9 cu. Ft., 110V unit, is built to meet the stringent storage needs of temperature-sensitive materials across scientific and research laboratories. Known for supplying modular casework, epoxy resin countertops, fume hoods, sink bases, and mobile carts, Government Lab Enterprises serves a wide range of industries—including education, pharmaceuticals, biotechnology, and environmental science. The company emphasizes laboratory infrastructure that not only complies with regulatory requirements but also offers long-term durability and flexible workspace design. The addition of the Arctiko SF150 addresses a growing demand among clients for reliable cold storage in compact laboratory settings. As ultra-low temperature storage becomes increasingly critical for sample integrity, vaccine preservation, and long-term research, products like this chest arctiko freezer are a necessary component of modern lab environments. "Storage solutions must evolve alongside the scientific work they support," said a company spokesperson. "Integrating ultra-low temperature options such as Arctiko freezers ensures that our clients maintain the highest standards in biosample preservation and regulatory compliance." Designed for both function and efficiency, the Arctiko freezer supports temperatures as low as -60°C, making it suitable for applications requiring stringent thermal control. Its compact footprint enables it to fit seamlessly into laboratories where space is at a premium without compromising performance or reliability. This freezer joins a carefully curated selection of laboratory infrastructure products intended to streamline operations and support scientific discovery. Government Lab Enterprises maintains a focus on function-driven design, enabling research environments to remain organized, safe, and efficient. "As laboratories face increased demand for environmental control, our role is to support those needs with well-matched equipment and furnishings," the spokesperson added. "Arctiko freezers are a solid match for clients aiming to uphold both research precision and regulatory standards." Government Lab Enterprises continues to support laboratory innovation through product selections that emphasize operational effectiveness. By offering the Arctiko SF150 chest freezer, the company reinforces its role in equipping labs with trusted, compliant, and versatile solutions for their most sensitive materials.
- August 14, 2025Science
Yamaha Motor Begins Joint Research Using Cell Handling Technology with a national research institute - Advancing Next-Generation Automated Experimentation to Promote DX and AX in Research -
Yamaha Motor Co., Ltd. (Tokyo: 7272) announced today its signing of a joint research agreement with RIKEN, a National Research and Development Agency, regarding the application of next-generation cell handling and automation technologies using cell picking and imaging systems. This joint research aims to develop technologies and infrastructure that promote digital transformation (DX) and AI transformation (AX) in research settings. By combining the automation and analysis technology of the RIKEN Center for Biosystems Dynamics Research*¹ (BDR) with Yamaha Motor's cell observation and handling technologies, and utilizing AI, the goal is to standardize work, improve accuracy, and obtain highly reproducible data. The joint research project is scheduled to run from July 2025 to March 2027. This research will focus on developing APIs (Application Programming Interfaces) and data integration platforms that enable the coordination of research equipment software and programs, as well as advancing cell observation and handling technologies. In this collaboration, Yamaha Motor will implement the methodologies and designs developed by RIKEN BDR, and the two parties will work together to explore the social implementation of advanced cell experimentation. These efforts are expected to lead to outcomes such as the establishment of high-precision cell selection technologies, the realization of full automation, and the development of new research approaches through sophisticated cell handling. To meet diverse needs of life science research sites and the growing demands for automation, Yamaha Motor aims to gain further insights through this research to support future functional development and implementation. The Company also develops and provides systems designed for the high-speed, high-precision handling of cell clusters*² and acquisition of image data. These systems feature functions such as automatic cell selection and automatic stitching of surrounding images, aiming to enhance efficiency in research workflows and improve the reliability of collected data. *1 RIKEN Center for Biosystems Dynamics Research (RIKEN BDR): https://www.bdr.riken.jp/en/ *2 Cell clusters refer to single cells or 3D cellular structures such as spheroids and organoids.
- August 14, 2025Science
Fujifilm and HORIBA Co-developed Gene Delivery System to Enhance Productivity in Gene Therapy Manufacturing
FUJIFILM Corporation (President and CEO, Representative Director: Teiichi Goto) and HORIBA, Ltd. (President: Masayuki Adachi) today announced the co-development of a novel gene delivery system that significantly enhances productivity in the manufacture of gene therapy products. Fujifilm has developed the industry’s first*1 continuous electroporation technology*2, which enables high-efficiency gene delivery into cells during the manufacturing process for gene therapy products, boosting productivity by approximately 100 times*3 greater compared to conventional methods. HORIBA played a key role in integrating this technology into a system and plans to release the finalized device to the global market in 2026 or later. Gene therapy is an approach that uses biotechnology to introduce functional genes into the body, targeting the root cause of genetic disorders. This technology is attracting global attention for its potential in treating intractable diseases that currently lack effective treatment options. Although the global cell and gene therapy market is projected to grow at a compound annual growth rate of approximately 30% through to 2030*4, several challenges remain. These include overcoming the technological complexities and inefficiencies of current manufacturing processes as well as high costs associated with research and development. To address these challenges, Fujifilm and HORIBA, two companies with extensive expertise in the life sciences field, joined forces to develop a gene delivery system designed to enhance manufacturing productivity and reduce costs. The development process leveraged Fujifilm’s advanced technologies and process control expertise, honed across a broad range of business fields including biopharmaceuticals, while HORIBA contributed its extensive manufacturing expertise and global support capabilities for industrial applications to oversee the design and production of the system. Following its commercial launch, HORIBA will lead sales and support efforts, focusing on the North American and European markets, where demand for the gene therapy is particularly high. By combining their respective strengths to develop and roll out this system, Fujifilm and HORIBA aim to help solve the pressing societal challenge of unmet medical needs. Background of the Co-Development Project Fujifilm and HORIBA have a history of collaboration across a variety of fields, including bioscience and semiconductors. The two companies have previously engaged in joint research, including those using HORIBA’s sensor technologies to improve the efficiency of pharmaceutical production processes. In 2023, the two companies launched a joint project to develop a gene delivery system (continuous electroporation system) in order to address production challenges in the growing field of gene therapy products. The Continuous Electroporation System Overview of the Continuous Electroporation System In the manufacture of gene therapy products, which involves the introduction of genes into cultured cells, improving the efficiency of the gene delivery process is key to increasing overall productivity. The conventional method, which relies on chemical reactions transfection reagent, faces efficiency challenges due to the complex chemical reactions involved and the difficulty in controlling the interactions between cells and reagents. Fujifilm’s innovative continuous electroporation technology, which was utilized in the project, address these limitations. By applying precisely controlled electrical pulses to cell membranes, it creates minute pores that allow genes to be directly delivered into the cells, significantly enhancing gene delivery efficiency. Furthermore, the system operates in a continuous flow, offering flexibly to adjust throughput and handle production on both small to large-scale. Compared to conventional batch-based methods, this continuous electroporation system can achieve up to 100 times greater productivity, contributing substantially to both manufacturing efficiency and cost reduction in gene therapy production. Conventional Method Gene delivery performed using PEI*5 as a chemical transfection reagent Fujifilm’s Continuous Electroporation Technology Cells suspended in liquid are continuously passed through an electroporation unit where electrical pulses are applied, creating pores in the cell membranes via which genes can be injected directly Comment from Toshihisa Iida, Director, Corporate Vice President, General Manager of Life Sciences Strategy Headquarters At Fujifilm, we are dedicated to supporting pharmaceutical companies and patients through integrated solutions across the drug development lifecycle, guided by our "Partners for Life" principle. The implementation of continuous electroporation technology marks a major step forward, improving gene delivery efficiency while addressing manufacturing cost challenges. By combining Fujifilm's advanced technologies with Horiba's manufacturing expertise, we aim to create a future where gene therapy drugs are accessible to more patients. Through continuous innovation, we strive to advance healthcare and improve the well-being of people around the world. Comment from Masayuki Adachi, President of HORIBA I am delighted that we have succeeded in developing a continuous electroporation system based on Fujifilm’s outstanding technology. The Bio & Healthcare field is essential to future growth, and going forward we will leverage our strength in analytical and measurement technologies, data management capabilities, and global support infrastructure, which we have cultivated in high-volume manufacturing fields such as automotive products and semiconductors, to accelerate the commercialization of this system, thereby contributing to better health and quality of life for many people. *1 Based on research conducted by Fujifilm. *2 A technology that uses controlled electrical pulses to create minute pores in cell membranes, allowing genes to be directly delivered into cells. This enables high-efficiency gene delivery and is anticipated to enhance productivity while reducing costs in the manufacture of gene therapy products. This technology was presented at the 26th Annual Meeting of the American Society of Gene & Cell Therapy held in Los Angeles, U.S., in 2023. *3 Based on internal studies by Fujifilm. Compared to conventional chemical transfection using PEI reagents (as of August 7th, 2025). *4 Estimate by Fujifilm based on data provided by Evaluate Pharma®, January 2025. *5 PEI: Polyethylenimine, a type of polymeric material used as a reagent for delivering genes or proteins into cells. * Please note that the contents including the product availability, specification, prices and contacts in this website are current as of the date of the press announcement and may be subject to change without prior notice.
- August 11, 2025Science
Breaking Boundaries in Stroke Imaging: The World’s First Clinical CT with a Curved Detector
When we set out to design the Micro-X Head CT , our goal was simple: to bring stroke diagnosis to patients faster, whether in an ambulance, a rural clinic, or a hospital emergency bay. But achieving this meant rethinking how CT scanners work at a fundamental level. In conventional CT scanners, flat-panel detectors rotate around the patient on large gantries. These systems are incredibly effective but they’re also heavy, expensive, and mechanically complex. That makes them impractical for mobile environments where space, weight, and speed are critical. To build a system compact and lightweight enough for stroke diagnosis on the move, we needed to do something never done before: create a curved detector. Why Curved Matters With a curved detector, we could achieve wide angular coverage using a fixed gantry.That meant we could eliminate the need for heavy rotating parts while still capturing high-quality projection images from multiple angles. It was a breakthrough in reducing size, weight, and power requirements, making the Head CT faster, lighter, and more portable. But here’s the catch: there are no off-the-shelf curved X-ray detectors suitable for clinical CT imaging. Curved detectors have been explored in research or industrial uses (like inspecting pipelines), but not in medical imaging. So, we had to build one from scratch. Head CT under development Partnering for Innovation We partnered with FUJIFILM to co-develop a custom solution, leveraging their flexible scintillator substrate - the same material they use in their flat panel detectors. Our team worked closely with theirs to overlap two scintillators into a seamless curved array, paired with a dynamic readout system capable of capturing multiple exposures rapidly. This was crucial for integrating with our proprietary NEX technology and enabling fast reconstruction. With further refinement, we engineered a new version of the detector using FUJIFILM’s technology, redesigned by Micro-X to be even smaller and lighter to achieve a72% weight reduction from the initial prototype. That’s a huge win for mobility, especially when every gram counts in a portable CT system. Solving the Complex Challenges Introducing a curved detector came with its own imaging and mechanical hurdles. Traditional reconstruction algorithms weren’t built to handle curved geometry, leading to inconsistencies and image artifacts. So we teamed up with Johns Hopkins University who are experts in computational imaging to develop new methods that solve these problems head-on. Combined with Micro-X’s NEX technology, which precisely controls X-ray sources without mechanical motion, we’ve built a system that can acquire multiple projection images in rapid succession, all without a rotating gantry. The Micro-X Head CT for stroke diagnosis includes a world-first curved detector A World-First Achievement To our knowledge, the Micro-X Head CT is the first CT scanner designed for clinical use to feature a curved detector. It’s a major technical milestone - not just for us, but for the future of portable medical imaging. As an engineer, it’s been incredibly rewarding to push the boundaries of what’s possible in medical imaging. But what’s most meaningful is knowing this technology will have a real-world impact — transforming how and where people receive life-saving stroke care.
- August 6, 2025Science
SyntecBioFuel Lab Expands Hiring and AI Infrastructure
SyntecBioFuel Lab, a leading developer of AI-powered sustainable fuel technologies, today announced a major expansion of its global workforce and high-performance AI infrastructure to meet growing demand for scalable biomanufacturing and low-carbon energy solutions. Strategic Hiring Push Across R&D, AI, and Engineering As part of its accelerated growth plan, SyntecBioFuel Lab is hiring over 120 new employees across multiple disciplines—including AI/ML engineering, synthetic biology, process automation, fermentation science, and commercial strategy. These new hires will be deployed across its R&D campuses in Cambridge, Massachusetts, and its newly expanded operations center in Seoul, South Korea. “SyntecBioFuel is on a mission to redefine how the world produces energy,” said Dr. Helena Kim, Chief Operating Officer at SyntecBioFuel. “Our team is rapidly growing to support our next-generation AI biomanufacturing platform and to bring clean fuels to global markets faster and more efficiently.” AI Supercomputing Cluster: 1,200 GPUs and Counting The hiring surge is accompanied by a significant expansion of SyntecBioFuel’s AI infrastructure, including the deployment of a dedicated AI supercomputing cluster powered by more than 1,200 GPUs. This system supports accelerated strain design, metabolic modeling, process simulations, and digital twin operations for large-scale fermentation optimization. The investment enables the lab to reduce R&D timelines by over 60%, optimizing workflows from microbial engineering to pilot-scale validation and regulatory compliance. Biomanufacturing Scale-Up in Progress SyntecBioFuel Lab is currently scaling its AI-enabled platform to produce drop-in biofuels such as sustainable aviation fuel (SAF) and renewable diesel, targeting commercial production by mid-2026. The platform combines data-driven metabolic engineering with continuous bioprocessing, aiming to improve yield, reduce carbon intensity, and lower the levelized cost of production. This effort aligns with SyntecBioFuel’s 2025 global forecast report, which projects the global biofuels market to reach USD 208 billion by 2030, driven by policy mandates, demand for decarbonization, and technological advances. Supporting the Clean Energy Workforce of the Future To attract top-tier global talent, SyntecBioFuel Lab is offering hybrid work options, long-term career development tracks, and equity participation in its clean energy mission. Positions are open to recent graduates, experienced specialists, and PhDs with backgrounds in biotechnology, artificial intelligence, data science, and chemical engineering. Interested applicants can explore opportunities at syntecbiofuel.com/careers About SyntecBioFuel Lab SyntecBioFuel Lab is a biotechnology company pioneering AI-enabled biomanufacturing for low-carbon fuels. Headquartered in Cambridge, MA, with operations in Seoul, South Korea, the company integrates synthetic biology, machine learning, and advanced fermentation systems to develop scalable alternatives to fossil fuels.
- August 4, 2025Science
Odyssey Math Tuition Unveils Cutting-Edge Junior College 2 Online Math Tuition E-Learning System in Singapore, Featuring Personalized Math Tuition Lessons, 24/7 Access, Interactive Worksheets, and Progress Tracking for Exam Success
Odyssey Math Tuition is proud to announce the launch of its innovative 24/7 E-Learning System, specifically designed for Junior College 2 Math Tuition (JC 2 Math Tuition). This online platform aims to revolutionize math education by offering students unparalleled access to high-quality math tuition resources, anytime and anywhere. Led by Mr. Justin Tan, a seasoned math tutor with over 13 years of experience in math education, the new Math Tuition E-Learning System is part of Odyssey Math Tuition’s commitment to providing comprehensive and effective math education solutions for students across all levels, from primary to junior college. Mr. Justin Tan, Founder and Lead Math Tutor of Odyssey Math Tuition, stated, “We are thrilled to introduce our 24/7 E-Learning System for JC2 Math Tuition. This platform represents our commitment to innovation in education, providing students with the tools they need to succeed in their A-Level examinations and beyond. With over 13 years of experience, I have seen firsthand the challenges students face, and I believe this e-learning system will make a significant difference in their learning journey.” The JC2 Math Tuition E-Learning System is meticulously crafted to align with the A-Level syllabus, ensuring that students master essential concepts and develop critical problem-solving skills necessary for excelling in their examinations. With this launch, Odyssey Math Tuition reinforces its position as a leader in the Singapore Math Tuition industry, offering both traditional math tuition classroom settings and cutting-edge online math tuition learning options. Enhancing JC2 Math Tuition with Exam-Focused Training At the core of Odyssey Math Tuition’s JC2 program is a focus on exam readiness. The curriculum is designed to cover the A-Level syllabus comprehensively, with a particular emphasis on high-yield exam questions that frequently appear in past papers. Through regular timed drills and full-length mock examinations conducted under realistic exam conditions, students hone their speed, accuracy, and time management skills—vital for success in the high-stakes A-Level tests. The program also incorporates personalized feedback mechanisms, allowing students to identify and correct recurring mistakes. By systematically revisiting challenging topics, students build a robust understanding and confidence in their abilities. This structured approach ensures that students not only prepare for exams but also develop a deep appreciation for mathematics. Revolutionizing Math Tuition: 24/7 E-Learning for JC2 Students The cornerstone of Odyssey Math Tuition ’s new offering is its 24/7 E-Learning System, which provides students with unlimited access to a wealth of educational resources. This includes interactive video lessons based on Odyssey Math Tuition’s proprietary curriculum, which simplifies complex mathematical concepts into digestible steps. Practice quizzes and topical tests allow students to reinforce their learning and assess their understanding. The platform is designed to be user-friendly, allowing students to learn at their own pace and according to their own schedules. Advanced tracking features monitor individual progress, highlighting strengths and areas that need improvement. This data-driven approach enables math tutors to provide targeted support, ensuring that each student receives the attention they need to succeed. Moreover, the E-Learning System features a variety of tools designed to enhance learning. Students can access pre-recorded video lectures that cover each topic in depth, with the ability to pause, rewind, and revisit sections as needed. Interactive quizzes and exercises allow students to test their understanding and receive immediate feedback. Additionally, the system includes a forum where students can ask questions and engage with peers and tutors, fostering a collaborative learning environment. The platform also offers progress tracking, where students can see their improvement over time and identify areas that require more attention. This data is also accessible to parents, who can monitor their child’s learning journey and provide support where necessary. Benefits for Students Enrolling in Junior College 2 Math Tuition Students entering JC2 face a demanding academic environment, where A-Level Mathematics becomes increasingly rigorous and time-sensitive. Enrolling in a structured JC2 Math Tuition program can provide a stabilizing influence during this critical year. One of the key advantages is the focused preparation that aligns directly with examination requirements. Rather than navigating the syllabus independently, students benefit from expert-guided instruction that prioritizes recurring question types, common pitfalls, and strategies for tackling challenging problems under time pressure. Another significant benefit is the opportunity for consistent reinforcement. As topics in JC2 often build on foundational concepts introduced earlier, tuition helps bridge any knowledge gaps while reinforcing prior learning. With the added complexity of integration techniques, differential equations, and applications of calculus, personalized guidance ensures that students can internalize concepts more effectively and apply them accurately during assessments. In addition, students gain access to a collaborative learning environment—whether online or in person—where they can clarify doubts, discuss problem-solving approaches, and receive tailored feedback. This not only strengthens content mastery but also cultivates critical thinking and mathematical resilience. The structured progression offered by a tuition program keeps students accountable to a regular study routine, reducing the likelihood of last-minute cramming and exam anxiety. For those who utilize the 24/7 E-Learning System, the flexibility of accessing resources on demand further enhances independent learning. Students can revisit difficult topics, revise at their own pace, and track their own progress, reinforcing a sense of ownership over their academic journey. Combined with classroom sessions and mock exams, the tuition program supports a holistic and adaptive learning experience, increasing students’ confidence and preparedness as they approach the A-Level exams. Comprehensive Math Tuition Across All Levels While the new E-Learning System is particularly geared towards JC2 students, Odyssey Math Tuition offers a full spectrum of math tuition services for students from primary school through to junior college. Their programs are designed to build a strong foundation in mathematics from an early age, ensuring that students are well-prepared for more advanced studies. For primary school math tuition students, Odyssey Math Tuition provides engaging and interactive lessons that make learning math fun and accessible, focusing on foundational skills in arithmetic, algebra, and geometry. Secondary school students benefit from specialized tuition that aligns with the MOE syllabus, offering targeted support in challenging topics like trigonometry and calculus to prepare for O-Level examinations. At the junior college level, the tuition covers H1 and H2 Mathematics, providing intensive training to achieve top grades in A-Level exams. The 24/7 Math Tuition E-Learning System complements these in-person classes, offering additional resources and practice materials that students can access at any time. This blended learning approach combines the personal interaction and immediate feedback of classroom tuition with the flexibility and convenience of online learning, making it an ideal solution for students seeking comprehensive math tuition in Singapore .
- July 31, 2025Science
Creative Proteomics Launches Plant Untargeted Metabolomics Service to Overcome Key Analytical Challenges in Botanical Research
Creative Proteomics today announced the launch of its advanced Plant Untargeted Metabolomics service, a specialized offering designed to provide researchers with comprehensive, high-resolution profiling of the plant metabolome. The service directly addresses the inherent analytical challenges of plant systems, characterized by immense chemical diversity and a wide dynamic range of metabolite concentrations. This new service moves beyond conventional metabolite profiling by integrating a multi-platform strategy centered on state-of-the-art Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) systems. Recognizing that no single analytical method can capture the entirety of the plant metabolome—estimated to exceed 200,000 unique molecules—Creative Proteomics employs a suite of high-performance instruments, including Thermo Fisher Orbitrap Exploris™ and Q Exactive™ series mass spectrometers for high-resolution accurate mass (HRAM) detection, and AB Sciex QTRAP® systems for high-sensitivity quantification. This approach ensures robust coverage of diverse chemical classes, from polar primary metabolites to nonpolar lipids and specialized secondary metabolites. "The challenge in plant metabolomics isn't just detection; it's achieving comprehensive coverage and meaningful biological interpretation," stated the Head of Metabolomics at Creative Proteomics. "A plant's metabolic state is a dynamic footprint of its genotype and its interaction with the environment. Our platform is engineered to capture that footprint with exceptional detail. By optimizing extraction protocols for different tissues and leveraging multiple chromatographic separations and mass spectrometry modes, we minimize analytical bias and deliver a dataset of superior depth and quality." A key component of the service is its sophisticated bioinformatics pipeline. Following data acquisition, the raw data undergoes rigorous processing, including peak deconvolution, alignment, and normalization. The service then provides advanced statistical analysis, including multivariate pattern recognition methods such as Principal Component Analysis (PCA) and Orthogonal Partial Least Squares-Discriminant Analysis (OPLS-DA), to identify statistically significant metabolic alterations between experimental groups. Subsequent metabolite identification is performed against extensive libraries, and pathway analysis tools like KEGG are utilized to place these changes into a biological context. The service is tailored for a range of advanced research applications, including: Functional Genomics: Elucidating gene function by characterizing the metabolic phenotype of mutants or transgenic lines. Crop Science: Identifying metabolic quantitative trait loci (mQTLs) and biomarkers for stress resistance, yield, and nutritional value. Plant-Microbe Interactions: Mapping the metabolic crosstalk between plants and pathogens or symbionts. Natural Product Discovery: Systematically screening plant extracts for novel bioactive compounds. With this technically advanced service, Creative Proteomics provides the global plant science community with a powerful tool to generate novel hypotheses, validate genomic data, and accelerate the pace of discovery. About Creative Proteomics Creative Proteomics is a specialist contract research organization (CRO) providing robust services in proteomics, metabolomics, and bioinformatics. Through a commitment to cutting-edge technology and scientific rigor, the company empowers academic, pharmaceutical, and agricultural research worldwide.
- July 18, 2025Science
Veljko Milkovic Wins 2025 Global Recognition Award for Revolutionary Self-Heating Ecological House
Serbian inventor and latest 2025 Global Recognition Award recipient Veljko Milković has developed a groundbreaking self-heating ecological house that maintains optimal indoor temperatures year-round without requiring conventional heating or cooling systems. The innovative dwelling, located in Novi Sad, utilizes passive solar design principles, earth integration, and thermal mass to create a completely energy-independent living space. Photo Courtesy of Veljko Milkovic The self-heating ecological house represents a significant advancement in sustainable architecture, addressing growing concerns about energy consumption and environmental impact in residential construction. Milković's design incorporates south-facing orientation for maximum solar gain, partial earth sheltering for natural insulation, and glazed greenhouse-style sunrooms that trap heat during winter months while maintaining comfortable temperatures in summer through natural ventilation systems. The housing concept addresses critical challenges facing the construction industry as energy costs continue to rise globally. Recent data reveals that residential buildings account for approximately 40% of total energy consumption in developed countries, with heating and cooling systems representing the largest portion of household energy use. Milković's design eliminates this consumption entirely through its innovative passive approach. " The self-heating ecological house demonstrates that comfortable living can be achieved without dependence on fossil fuels or expensive HVAC systems ," Milković notes, " through careful integration of natural materials and solar orientation, the structure maintains temperatures between 18-22 degrees Celsius throughout the year with zero energy input for climate control. " The construction utilizes locally sourced, environmentally friendly materials, including clay, straw, and wood for insulation, significantly reducing both construction costs and carbon footprint. The thick insulating walls store thermal energy during daylight hours and release it gradually, creating stable indoor conditions. Earth berming around portions of the structure provides additional insulation while the thermal mass of walls and floors regulates temperature fluctuations. Technical specifications include strategic placement of glazing panels on the south wall to create a solar atrium effect, natural ventilation systems that ensure healthy air circulation without heat loss, and careful material selection that maximizes thermal performance. The design requires no mechanical heating or cooling equipment, resulting in utility costs that are virtually eliminated for temperature control. Construction costs for the ecological house remain significantly lower than conventional buildings, with estimates indicating total project costs for a complete dwelling to be around 10-20% cheaper than for the traditional houses. This cost-effectiveness stems from the use of local materials, simplified construction techniques, and the elimination of expensive mechanical systems typically required for climate control. The project has attracted attention from environmental organizations and green architecture institutions across Europe. Milković's approach aligns with European Green Deal initiatives promoting sustainable construction practices and reduced energy consumption in residential buildings. The design offers particular relevance as governments worldwide implement stricter energy efficiency standards for new construction. Veljko Milković, who holds 31 granted patents and has received multiple Energy Globe Awards, brings decades of experience in sustainable technology development to this housing innovation. His previous recognition includes the Tesla Spirit Award 2024 for realizing Nikola Tesla's vision of gravity-powered machines and national Energy Globe Awards in 2010 and 2011 for ecological innovations. The self-heating house concept can be adapted to various climates and geographical locations, with modifications to orientation, insulation thickness, and glazing area based on local conditions. Construction typically requires 6-8 months, followed by a full year of monitoring to document seasonal performance and energy efficiency. "This housing model proves that traditional building wisdom combined with modern understanding of thermal dynamics can create living spaces that work in harmony with natural systems rather than fighting against them," Milković concluded. "The technology exists today to build homes that require no external energy for comfort, representing a practical solution for sustainable development." About Global Recognition Awards Global Recognition Awards is an international organization that recognizes exceptional companies and individuals who have significantly contributed to their industry.
- July 18, 2025Science
The Power of Graphene for a Greener Infrastructure: Agile Energetics Electronics and Voltek Ace
Shireen Bojja, an expert in public safety power electronics has been honored with a 2025 Global Recognition Awar d. As the Engineering Manager for Agile Energetics Electronics LLC, Bojja contributed significantly towards the development of the graphene-based energy storage technology. Bojja's achievement represents a significant milestone in sustainable energy technology, particularly by developing the next-generation graphene-enhanced energy storage systems and SuperPower GPRC algorithm app for use with the energy storage module. Her work addresses critical limitations of legacy battery technologies by offering quick charging capabilities, extended operational life, and stable performance across extreme temperature ranges. The contributions have an impact across leadership, research, innovation, and mentoring categories, particularly emphasizing the international scope to power electronics advancement. Photo Courtesy of Agile Energetics Electronics LLC Technical Innovation and Graphene Technology Leadership Bojja’s early career as a design engineer developing navigation systems and 900 MHz radio systems for use in Caterpillar dozers supporting heavy highway infrastructure laid the foundation for her current focus on the traffic industry and the advancement of graphene technology for intelligent transportation system (ITS) applications. Her transition from Silicon Valley to Southern California as a technical engineering consultant began her entrepreneurial journey, where she demonstrated an exceptional ability to bridge complex technical innovation with practical market applications. Under her guidance, the development of Graphene Hybrid Supercapacitor technology represents a paradigm shift in energy storage solutions that addresses the limitations of traditional lead-acid batteries. The SuperPower GPRC algorithm provides real-time optimization and operational modeling capabilities, enabling engineers to visualize runtime performance instantly and maximize efficiency across installations. The graphene hybrid supercapacitor modules support over 20,000 charge-discharge cycles while fully recharging in under 10 minutes, demonstrating superior performance to conventional battery technologies. These non-toxic modules operate across a wide temperature range from -30 degrees Celsius to +70 degrees Celsius, eliminating hazardous leakage risks and enabling safe deployment in roadside cabinets, fleet depots, and remote installations. Research Excellence and Industry Impact Currently pursuing a doctorate in business administration, Bojja's academic endeavors reflect her commitment to integrating research methodologies with practical business applications while focusing on small business growth and sustainability. Her research demonstrates the ability to combine technical innovation with business scalability considerations, particularly in developing frameworks that help enterprises navigate complex technological transitions. Furthermore, California Manufacturing Technology Consulting supported the development of graphene hybrid supercapacitor technology through the CMA+ program, which is part of the U.S. Department of Commerce's Manufacturing Extension Partnership. Sustainable Technology Development and Market Applications Bojja's graphene hybrid energy storage work represents more than a technological upgrade, as it constitutes a fundamental shift toward greater resilience and sustainability in public infrastructure development. Her SuperPower series energy storage solutions powered by graphene hybrid supercapacitor technology deliver rapid charging, extended life, and stable operation, making them ideal for systems that demand reliability and low maintenance. Field testing of these modules is currently underway in critical-use scenarios, including intelligent transportation systems and U.S. Department of Transportation applications, with initial observations highlighting the potential for reduced maintenance costs and increased uptime. The cost-benefit analysis over 10 years demonstrates that lead-acid batteries incur recurring costs every two years with stark increases over time, while graphene hybrid supercapacitor modules require only a one-time fee with no replacements needed over the same period. This technology exhibits dramatically higher life cycles than traditional lead-acid batteries across all depths of discharge, with improvements ranging from over 12,000 percent at 100 percent depth of discharge to more than 90,000 percent at 20 percent depth of discharge. For public sector adoption, Agile Energetics Electronics has end-of-line production capabilities in California to ensure that GHSC modules can support Build America, Buy America (BABA) compliance requirements to meet grant guidelines while avoiding delays and cost overruns. Final Words Alex Sterling from Global Recognition Awards noted the significance of Bojja's contributions to electrical engineering and sustainable technology development. "Shireen Bojja's recognition represents a commitment to advancing sustainable energy solutions while creating practical applications for complex infrastructure challenges," Sterling remarked. "Her technical expertise in developing graphene-enhanced energy storage systems, combined with her entrepreneurial leadership and mentoring impact, embodies what this recognition represents in terms of breaking technological barriers and fostering innovation that addresses real-world sustainability needs." Her work continues to influence critical infrastructure development while setting new paradigms for sustainable energy storage solutions in transportation, industrial, and public sector applications. The recognition highlights her role as a trailblazer who graduated with a master's degree in electrical engineering from California State University-Fresno and became the first female engineer in the R&D at Trimble Navigation in 22 years, demonstrating her steadfast commitment to innovation, sustainability, and breaking barriers in the science, technology, engineering, and mathematics fields. About Global Recognition Awards Global Recognition Awards is an international organization that recognizes exceptional companies and individuals who have contributed significantly to their industry.
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