World News
Bin Li Contributes New Data-Driven Model Integrating BOM and ECBOM for Manufacturing Energy Analysis
Green transformation in manufacturing is becoming a global focus. To address shortcomings in current single-dimensional energy evaluation methods, the study proposes a digital twin-based assessment approach. The method uses BOM and ECBOM data to integrate energy consumption characteristics across virtual and physical spaces throughout the manufacturing lifecycle. Research results show that this approach improves the accuracy of energy efficiency assessment, with BOM and ECBOM serving as key data links. The framework offers manufacturers a unified method for quantifying energy use across physical and virtual environments. The study constructs a five-dimensional energy-efficiency evaluation model that integrates physical entities, virtual entities, service systems, data fusion processes, and interconnection relationships within a digital twin framework. By using BOM and ECBOM as data links, the method supports the extraction, visualisation, and real-time application of energy consumption characteristics throughout the manufacturing service lifecycle. The framework enables a more accurate assessment of energy use in different stages and provides a basis for optimising manufacturing processes. Evaluation results show that the ECBOM model can reveal clear differences in energy consumption across components, allowing high-consumption links to be accurately identified. The data indicates that the spindle box body consumes 14.06 kilograms of standard coal equivalent and produces 20.12 kilograms of carbon dioxide, significantly higher than other parts. By converting production information from multiple BOM views into unified energy metrics, the method supports a comprehensive assessment of each production link and offers a basis for improving energy use across manufacturing processes. Contributing to this research is Bin Li, who is pursuing a Master of Arts in Climate and Society at Columbia University and holds a Bachelor of Science in Sociology from the University of California, Riverside. He has worked at Suzhou Walin New Energy Technology Co., Ltd., the Bureau of Ecology and Environment, the Environmental Planning Institute, and Dongqiao Centralised Sewage Treatment Co., Ltd., where he gained experience in pollution investigation, water quality analysis, environmental impact assessment, sustainability initiatives, sewage management, and ecological restoration. His academic background also includes case studies on the Bay Area Clean Air Plan and U.S. EPA regulations, supported by technical skills in Python, R, SQL, and data visualisation. The study demonstrates how a digital twin–based framework supports comprehensive energy consumption assessment. By establishing a five-dimensional model and a multi-view BOM-to-ECBOM conversion method, the research provides structured mechanisms for quantifying energy use throughout the manufacturing service lifecycle. These contributions enhance the accuracy of energy efficiency evaluation and offer a foundation for optimising high–energy consumption processes within manufacturing systems.
La Casetta delle Marche Transforms Into Italy's Leading Family Destination
Carrie’s Pilates Franchise Division Celebrates The Grand Opening Of Its 6th Location In Las Colinas, Texas
New Industry Insights Reveal Feedback Chaos as the Hidden Bottleneck in Product Development
- December 15, 2025Business
Meet the New Benchmark in Global Automotive Safety, GEELY OPENS WORLDS LARGEST VEHICLE TESTING CENTRE
New Geely Safety Centre sets five new Guinness World Records for size, scope and capability Geely Safety Centre offers fully capability for new tests for the electrified and intelligent vehicle era Cybersecurity, data privacy protection, health, and environmental protection included in Geely’s new concept of Comprehensive Safety Geely Safety Centre becomes new platform for collaboration with global partners on safety technologies and standards Geely Auto Group today unveiled the Geely Safety Centre, now the world’s largest and most advanced automotive safety testing facility. The safety center spans an area of 45,000 m², with an initial investment of over 2 billion RMB, enabling Geely to accelerate the innovation of safety technologies and elevate global safety benchmarks. The Geely Safety Centre covers the full spectrum of global safety testing, from high-speed crash tests and pedestrian protection to active safety simulations, battery and new energy powertrain safety, cybersecurity, and health-related safety evaluations. Going beyond just the standard vehicle and occupant safety tests, the new centre has been built to support Geely’s “comprehensive safety” for the intelligent vehicle era. The centre comes with new capabilities such as cybersecurity testing to meet CNAS-certified standards, multiple attack vectors, and evaluation for chips, firmware, data transmission and encryption, OTA updates, vehicle sensors and controllers, etc. Safety for Geely goes beyond just products and vehicles, human and environmental health is also an important aspect of safety which the centre can test for. Geely’s Safety Centre’s “Golden Nose” team focus on testing for volatile materials and odors, detection of harmful substances, and ensuring products meet a “zero harmful gas/odor” standard. The new Safety Centre has also set five world records, including: the largest (81,930.745 m²) automotive safety laboratory, the longest (293.39 meters) indoor car crash test track, the largest (28,536.224 m²) altitude-climate adjustable (snow/rain/solar radiation simulation) wind tunnel (250km/h max wind speed) facility for car testing, the largest (12,709.293 m²) arbitrary-angle (0-180°) car crash test zone, and the most tests (27 types) available in an automaker safety test laboratory. The new Safety Centre brings together global best practices in automotive safety development, combining insights from international safety leaders with Geely’s own rapidly advancing R&D capabilities to push safety performance beyond regulatory requirements. The centre also strengthens Geely’s collaboration with institutions such as CATARC and Tsinghua University, including the joint release of the White Paper on the Development of Intelligent Vehicle Safety. Together, these efforts reinforce Geely’s commitment to drive the next wave of safety innovation and raising industry benchmarks in the intelligent mobility era. Over the past decade, Geely has invested more than 250 billion RMB into R&D, with safety as a core priority. The launch of the Geely Safety Centre represents the next step in that commitment, enabling Geely to deliver safer, smarter, and more sustainable mobility solutions for users around the world. Jerry Gan, CEO of Geely Auto Group said “Safety has always been Geely Auto Group’s top priority over the past 30 years. We’ve always aimed to exceed national and regional standards to set new benchmarks in safety, is a benefit to everyone in the industry and consumers globally. With the new Geely Safety Centre, we open a new chapter for safety in the age of intelligent vehicles.” Li Chuanhai, Vice President of Geely Auto Group and Head of Geely Research Institute said “The global electric and intelligent transformation of the automotive industry requires new and higher standards of safety in both physical and digital spheres. The new Geely Safety Centre supports and accelerates the innovation of safety together with the collaborative efforts of safety technology leaders in the world.”
- December 15, 2025Business
American Twins Cash & Roman Felber Target British F4 Success with Fortec Motorsport
— Fortec Motorsport is pleased to confirm that identical twins Cash and Roman Felber will join the team for the 2026 Wera Tools F4 British Championship, certified by FIA. The American pair arrive in the UK following a standout year in the Ligier Junior Formula Championship on home soil, in which both drivers claimed race victories and multiple podiums. Cash concluded the series third overall in the standings with Roman seventh; the brothers also secured second and fourth respectively in the Rookie rankings. Cash & Roman Felber American Twins It was a season defined by momentum on both sides of the garage. Cash displayed front-running consistency through opening-lap assertiveness and composed late-race judgement, collecting six podiums and two wins. Roman recovered strongly from early-season mechanical setbacks to deliver five podiums, a victory, and two pole positions, showcasing equally powerful pace and progression. Racing has been a shared journey from the start. The brothers first drove at age eight on Segway karts around their driveway, but a visit to the 2022 United States Formula 1 Grand Prix ignited a commitment to pursue a career in motorsport. Since then, they have competed as rivals on track and made history in the LJFC as the first twin brothers in the series’ history to finish on the podium in the same race. The 2026 Wera Tools British F4 season begins at Donington Park on April 18–19, featuring 30 races across 10 meetings, including a return to Zandvoort in the Netherlands. Cash and Roman will compete with the support of BioLongevity Labs , iMerchant Solutions, Conversio Pay, Town Hall, and Rebol. Quotes: Oliver Dutton, Team Principal, Fortec Motorsport “Cash and Roman have shown us clean fundamentals, intelligent race craft, and the humility in debriefs that separates good drivers from championship contenders. We’ve seen what they did in the States. Now we’ll develop what they can become at the circuits that matter.” Cash Felber “The goal for 2026 is simple: arrive prepared, extract everything the car has, and leave no doubt. Fortec Motorsport’s attention to detail is exactly what I need in my career right now, and their engineering depth and coaching structure will help on the path to Formula 1.” Roman Felber “Wera Tools British F4 is the next test, and I’m bringing the same process from this season: learn fast, adapt faster, go quicker. The series rewards discipline and race intelligence—qualities I grew in abundance this year.” Enzo Mucci, Performance and Mindset Coach “I am delighted to see Roman and Cash come over to the UK to race. Having watched them on track, I am pleased to see how quickly they are adpating to the British F4 car. They are both looking very promising. I can’t wait to see them compete in 2026.” Partners for the Journey: BioLongevity Labs — A leading longevity science company creating advanced solutions that help people look, feel, and perform younger. Through cutting-edge research and premium formulations, BioLongevity Labs delivers innovative wellness products designed to boost energy, improve vitality, and support a longer, healthier life. iMerchant Solutions — A global payment service provider supporting enterprises across the world, iMerchant powers businesses with speed, precision, and reliability. “We are honored to support the Felber brothers in their Formula 4 journey—celebrating their passion, discipline, and drive to reach the top. Just as they race toward victory, we continue to innovate and accelerate the future of global payments,” stated Martin Khemmoro. Additional committed partners back for 2026: TownHall and Rebol. “Their belief underwrites everything from testing mileage to engineering depth,” noted Josh Felber. “They don’t just put logos on a car—they help build careers.” About British FIA Formula 4 The British FIA Formula 4 Championship is an FIA-certified entry point to international single-seater racing, recognized globally for competitive grids and professional team structures. The series has a proven record of developing drivers for the next steps on the Formula 1 pathway. About Fortec Motorsport Fortec Motorsport is one of the United Kingdom’s leading junior single-seater teams, competing across multiple categories with a track record of winning races and developing drivers for higher levels of the sport. The team is renowned for engineering depth, data-driven coaching, and a high-performance culture. About FLBR Motorsport FLBR Motorsport supports twin drivers Cash and Roman Felber with a program built on disciplined driver development, engineering rigor, and a people-first culture. From U.S. podiums to the European ladder, FLBR’s mission is simple: build champions the right way—technically, mentally, and ethically.
- December 15, 2025Business
New Market Report Reveals Key Trends, Multiples, and Strategic Insights in Manufacturing & Industrials M&A
Mergers & Acquisitions , a middle-market M&A advisory firm, today announced the release of its Manufacturing & Industrials M&A Multiples, Trends & Statistics Market Report , providing comprehensive analysis of M&A activity shaping the industrial and manufacturing sectors through 2025. The report delivers timely market intelligence on deal flow, valuation multiples, sector dynamics, and strategic themes influencing buyers and sellers across global markets. Compiled using extensive industry data and expert commentary, the report highlights what’s driving deal-making momentum and valuation shifts in a transforming industrial landscape. Key Findings Include: • Steady deal growth and rising capital deployment — Deal counts ticked up to 442 in Q2 2025 compared to 437 in Q1 2025 , while total invested capital remained robust at $17.5 billion . • Valuation multiples reflect divergent buyer dynamics — Strategic buyers commanded a median EV/EBITDA of 14.7× in 1H 2025, up from 8.0× in 2024, while private equity valuations moderated to 9.6× . • Private equity backing remains significant — Sponsors accounted for a five-year high share of invested capital even as deal counts dipped, showcasing larger platform investments. • Megadeals illustrate strategic transformation — Notable transactions analyzed include high-impact rail and industrial infrastructure combinations that are reshaping market structure and competitive positioning. Emerging Themes Identified: The report highlights several structural drivers shaping deal dynamics, including electrification and grid equipment, automation and smart manufacturing, logistics consolidation, and service/aftermarket monetization. It also examines regulatory considerations and how shifting buyer strategies are influencing valuation and integration execution. The report anticipates that "2025 continues to demonstrate resilience and evolution in industrial M&A activity heading into 2026, with strategic buyers willing to pay premium multiples for capability and scale, while sponsors deploy larger checks into platform roll-ups." The analysis also underscores the importance of recurring revenue models and digital-industrial convergence as core themes influencing investor appetite and valuation dynamics. The Manufacturing & Industrials M&A Multiples, Trends & Statistics Market Report is available now on MergersandAcquisitions.net . For executives, financial sponsors, and corporate development professionals navigating buy and sell-side M&A strategies, this report offers critical benchmarks and forward-looking insights to inform decision-making in a competitive deal environment. About MergersandAcquisitions.net MergersandAcquisitions.net is a leading source of market intelligence, insights, and analytics on global mergers and acquisitions activity across sectors. The platform provides research, commentary, and tools that help dealmakers, corporate strategists, and investors stay informed and make confident, data-driven decisions.
- December 15, 2025Business
RecyGlo and Wongpanit Partners with ERTH Ventures To Build Thailand’s First Integrated MRV To Digital Carbon Credits At National Scale
ERTH Ventures today announced a strategic collaboration with RecyGlo and Wongpanit, Thailand’s largest recycling network with over 2,000 branches processing approximately 1.5 million tons of recyclable materials annually . Together, the parties aim to build Thailand’s first end to end system that connects physical waste operations, digital carbon accounting and digital carbon credits on a transparent, verifiable infrastructure. RecyGlo and Wongpanit signed an MOU to merge digital carbon accounting with physical waste collection. This integration ensures end-to-end data tracking from bin to recycling plant, automating ESG reporting for manufacturers facing new EPR and Net Zero requirements. Under a new MOU between ERTH and RecyGlo, ERTH will add an AI driven MRV and blockchain timestamping layer on top of this data foundation, allowing high integrity recycling outcomes from Wongpanit’s nationwide operations to be converted into verifiable, traceable digital credits aligned with leading international carbon credit frameworks. From Waste Data To Verifiable Digital Credits Through this collaboration, ERTH will work with RecyGlo and Wongpanit to transform verified recycling outputs into globally credible climate assets by leveraging: End-to-end traceability data from Wongpanit's 2,000+ branches (Thailand and international) and digital tracking from collection to recycling plant ensure granular audit trails and reduced landfill leakage. Integrating automated carbon accounting using RecyGlo's Sana Terra platform with ERTH's MRV logic and blockchain timestamping infrastructure for issuing, tracking, and providing on-chain proof of origin, ownership, and retirement of carbon and related environmental credits. “This partnership structurally upgrades Thailand’s circular economy and climate finance,” stated Kendo Intuphuti, Founder and CEO of ERTH Ventures. “RecyGlo provides data, Wongpanit manages national waste flows, and ERTH converts every verified ton into transparent, globally recognizable carbon credits, meeting the increasing demands of sophisticated buyers and regulators.” RecyGlo’s co-founder and CFO, Okka Phyo Muang: “Integrating ERTH's MRV and timestamping with Wongpanit transforms environmental data into high-integrity assets. This partnership links national recycling with transparent digital carbon accounting and verifiable market instruments, positioning Thailand as a regional leader in credible, data-driven climate action and setting a new circular economy standard.” Governance And Compliance Focus To support this initiative, the project has established a governance-focused Advisory Board with expertise spanning environmental policy, digital-asset compliance, and cross-border climate markets. Advisors include Tom Duckworth (U.S. industrial climate advocate and philanthropist), Oak Suwanvichit (cross-border family-office advisor, ex-Apple, ex-T-mobile) and Daniel Bertoli (Harvard-trained financial strategist, ex-McKinsey). “As climate markets mature, the world will rely on digital credits backed by real data and transparent provenance,” said Tom Duckworth. “ERTH, RecyGlo and Wongpanit together are building the credibility layer that enables that future.” Following successful verification cycles and registry approvals, the collaboration is expected to expand across additional Wongpanit branches and partner networks, paving the way for a scalable, standards aligned circular economy infrastructure anchored in Thailand.
- December 15, 2025Business
Zeca Media Releases Report On How AI Tools Are Changing Customer Search Behavior
The latest resource from Zeca Media comes as AI summaries and zero-click search experiences become a dominant part of the customer journey, offering business owners a clearer understanding of the behavioral shifts affecting visibility and trust online. More details can be found at https://zecamedia.com/insights/how-ai-search-tools-are-changing-what-local-customers-expect-in-2026 Most customer decisions now occur before a business ever receives a call or form submission, says Zeca Media. As AI tools condense information into brief summaries and searchers skim results more quickly, customers often form early impressions in seconds, relying on small cues like clarity, relevance, and familiarity, to decide which provider to contact. This trend, as the agency notes, is collaborated by recent industry research which show that 62% of prospective customers now trust AI to guide brand decisions, highlighting the need for businesses to understand how to better position themselves to surface in these AI search results. “AI has changed how people read, interpret, and compare information. Customers decide who to contact based on the smallest cues, like a clear description, a consistent message, or a straightforward explanation of what a business actually does," Zeca Media explains. "Our articles help owners understand those decision points without jargon or marketing language.” For local businesses, Zeca Media recommends crafting clear, scannable product and service descriptions as those allow both prospects and AI tools to quickly get a sense of what the business is about. Maintaining consistent information across profiles, maps, and directories means the business is more likely to be surfaced when nearby customers search for related products or services, it notes. Zeca Media also explains that customers often compare two or three providers silently before making contact, scanning for simple indicators, such as customer reviews, recent activities, and examples that show the business is familiar with their situation. These cues reduce uncertainty and help the customer feel confident enough to take the next step and, since AI summaries rely heavily on patterns and repeated information, aligned messaging has become an even stronger trust signal than in previous years. As AI-driven search becomes more influential, Zeca Media says the businesses that present clear services, consistent messaging, and simple next steps will be the ones that earn first contact, even as traditional organic traffic declines. Zeca Media regularly publishes plain-language observations on local customer behavior, online communication patterns, and the influence of AI on search visibility. To read the full article or learn more about Zeca Media, please visit https://zecamedia.com/
- December 15, 2025Finance & Loan
iDenfy was recognized as a top ID verification platform at the global FF Awards 2025
iDenfy, a global RegTech platform known for its AI-powered identity verification and fraud prevention tools, earned a spot as a finalist in the “ID Verification & KYC” category at the FF Awards 2025. The company secured this recognition through a mix of online votes and expert evaluation that proved its superior service quality and wide compliance tools in fintech. This award helps to evaluate current market needs and push the online market toward more transparency and faster onboarding results for businesses to prevent fraud online. The FF Awards , is one of the most recognized among global fintech leaders annual event organized by FF News. The event took place in London, November 25th. The purpose of the awards ceremony was to showcase specific industry businesses and their technological innovations that have made a measurable impact on financial services. It combined public voting with the expert evaluation. The ceremony was attended by leading innovators across banking, payments, insurance, and digital identity firms. FFawards is known for its blend of industry insight and entertainment, and has become a key benchmark to evaluate how well the product is tailored in the fintech space. “The recognition among finalists at the FF Awards is a powerful validation of our work. The identity verification industry evolves rapidly, and organizations require solutions that are secure, accurate, and simple to implement. We are here to make it happen”, confidently expressed Domantas Ciulde, the CEO of iDenfy. Each submission to the FF Awards required a dedicated video presentation showcasing a company’s technology, mission, and differentiators. iDenfy highlighted throughout its video submission the complete identity verification package, advanced fraud prevention capabilities, and its primary objective to deliver safer online onboarding systems for companies. After progressing through a multi-stage review involving submission, approval, public voting, and expert evaluation, iDenfy earned a finalist position and received the official FF awards statue. The recognition arrives in a milestone year for the company. Earlier in 2025, iDenfy was named the leading identity verification provider in G2’s Winter report, supported by outstanding customer satisfaction and high performance across KYC, AML, and KYB services. This achievement strengthened the company’s reputation as a leading global provider of compliance technology for digital businesses. iDenfy’s verification platform offers a complete package of mixed fraud prevention services, powered by the latest artificial intelligence biometric recognition, more than 3000+ document analysis, risk scoring profiles, ongoing user monitoring management, and smooth workflow automation. These capabilities help organizations to verify millions of users in no time, while meeting regulatory standards across fintech, banking, blockchain, insurance, e-commerce, mobility platforms, and other high-risk sectors. “Being named as a finalist is a meaningful moment for us. Our partners trust us to deliver reliable compliance tools, and we work every day to justify that trust. Recognition from the FF Awards reinforces the value of our technology and encourages us to continue to minimize fraud for digital businesses worldwide,” added Robert Kotov, iDenfy’s Business Development Executive. It’s worth mentioning that iDenfy is one of the few KYC providers that also offers manual expertise and in-house KYC re-checks that improve false positives, which AI, unfortunately, can influence, no matter the solution. Identity checks are carefully done by the automated system as well as internal review support, to make sure that the documents matched with the identity, to avoid fraud patterns, and prevent system errors. Based on client requirements, every verification can be reviewed within three minutes with up to 99% accuracy.
- December 15, 2025Technology
HackerNoon and GPTZero Announce Partnership to Expand AI Transparency in Tech Publishing
HackerNoon , the community-driven technology publishing platform, announced today a partnership with GPTZero to integrate automated AI-detection disclosures across HackerNoon’s publishing workflow. Under the partnership, GPTZero’s AI detection will be applied to all submissions reviewed by HackerNoon’s editorial team, and AI usage disclosures will be displayed on published stories to provide readers with greater visibility into how content is produced. As part of the collaboration, GPTZero’s detection capabilities will be integrated into HackerNoon’s Editing Protocol to support editorial review of all blog submissions. HackerNoon also plans to use GPTZero-developed models, including Model 3.7b, to support research and reporting on trends related to AI and blogging over time. “We're building AI transparency infrastructure into how HackerNoon publishes because publishing standards matter more than ever,” said David Smooke, HackerNoon Founder/CEO. “GPTZero's proven AI detection technology analyzes every submission we review. With this partnership, our readers get more transparency, our editors get a reliable tool, and HackerNoon strengthens the tech stack of its publishing platform .” GPTZero provides AI detection intended to help identify text generated by widely used AI systems and can highlight sentences deemed AI-written. The integration will add disclosure elements to HackerNoon article pages, including sentence-level analysis beneath author bios and across relevant sections of the reading experience. The partnership is designed to support two goals: expanding transparency and trust in digital publishing at scale, and recognizing independent writers by preserving and acknowledging human creativity. “HackerNoon’s shaped how millions of people understand technology,” said Alex Cui, Cofounder and CTO, GPTZero. “GPTZero is excited to bring our AI detection technology to every HackerNoon article and give readers and writers a clearer view of how AI is used in online content. This collaboration adds sentence-level AI analysis beneath author bios and across article pages, supporting our mission to build the verification layer for the internet.” More About The Integration Under the partnership, all new submissions will be analyzed using GPTZero. HackerNoon editors review over 5,000 monthly submissions from more than 50,000 independent contributors, checking for AI usage before publication. Readers will be able to see whether the story is written by a human or assisted by AI, enabling trust in what they read. For media inquiries, interviews, or collaboration opportunities, please contact: Sheharyar Khan, [email protected] About HackerNoon How hackers start their afternoons. HackerNoon is built for technologists to read, write, and publish. We are an open and international community of 50k+ contributing writers publishing stories and expertise for 4M+ curious and insightful monthly readers. Founded in 2016, HackerNoon is an independent technology publishing platform run by David Smooke and Linh Dao Smooke. Start blogging about technology today. About GPTZero GPTZero is the most accurate and reliable AI detector trusted by more than 10 million users worldwide, including students, educators, writers, and professionals. It identifies text generated by models like ChatGPT, Claude, Gemini, and Grammarly and highlights AI written sentences with high precision. Organizations, publishers, and creators use GPTZero to verify authenticity, analyze writing, and bring transparency to digital content. Featured in the New York Times, Wired, and Harvard Business Review, GPTZero is building the verification layer for the internet. Try it for free today.
- December 15, 2025Science
CD Bioparticles Launches Comprehensive Animal mRNA Vaccine Solutions to Support Veterinary Research
CD Bioparticles, a leading manufacturer and supplier of numerous drug delivery products and services, has announced the launch of an advanced animal mRNA vaccine platform to accelerate the development of innovative and tailor-made vaccines for veterinary applications. This new offering includes solutions for sequence optimization, mRNA production, LNP formulation, and preclinical testing. In the field of animal health control, mRNA vaccine technology is spearheading a wave of innovation. Due to their rapid response, high-efficiency expression, and modulateability, mRNA vaccines are emerging as potent tools against emerging animal diseases. CD Bioparticles has extensive experience developing veterinary mRNA vaccines for RV, IBRV, BVDV, PRRSV, PEDV, FMDV, PRV, FIPV, FCV, FPV, and FHV. With extensive experience in mRNA sequence design and optimization, CD Bioparticles now provides scientists an advanced mRNA vaccine platform, to accelerate the development of innovative, cost-effective, and customized veterinary vaccines. These new services include sequence optimization, mRNA production, LNP formulation, analytical evaluation, and preclinical testing. The solutions will enable scientists' effective responses to the evolving landscape of animal health threats. CD Bioparticles offers a streamlined pathway from concept to preclinical readiness, including all critical stages of mRNA vaccine development. For example, CD Bioparticles provides the Vaccine Antigen Design and mRNA Sequence Optimization service, to design mRNA sequences for specific antigens that target prevalent viral strains. To enhance immune responses, these mRNA constructs may incorporate multiple antigens, antigen variants, signal peptides, and co-stimulatory signals. CD Bioparticles' proprietary algorithms then optimize the entire sequence, including untranslated regions (UTRs), coding regions (CDS), cap structures, and poly(A) tails, to maximize protein expression. CD Bioparticles specializes in Lipid Nanoparticle (LNP) Formulation and Delivery System Development. LNP formulations can be custom-developed to address species-specific requirements for veterinary applications. CD Bioparticles also offers multiple LNP platforms with adjustable particle size, surface modifications (e.g., polyethylene glycolization and targeting ligands), and stability testing. The company performs in vitro validation to assess LNP-mediated expression and encapsulation efficiencies using methods such as the RiboGreen assay, transmission electron microscopy, and dynamic light scattering. Other services, such as Biological Validation, mRNA Synthesis, Quality Control and Analytical Testing, and Pre-clinical Testing and Development are also available at CD Bioparticles. CD Bioparticles is capable of significantly reducing overall vaccine costs by supplying low-cost GMP-grade cap analogs and NTPs. In addition, CD Bioparticles can offer comprehensive preclinical testing platform for cells and animal models, which ensures a thorough evaluation of efficacy and safety before clinical trials. This new platform will enable researchers and pharmaceutical companies to respond quickly to emerging animal health threats by leveraging the speed and efficiency of mRNA technology. To know more information about these solutions for Animal mRNA Vaccines and other services for research applications, please visit https://www.cd-bioparticles.net/services/comprehensive-solution-for-animal-mrna-vaccines.html . About CD Bioparticles CD Bioparticles is an established drug delivery company that provides customized solutions for developing and manufacturing novel biocompatible drug delivery systems. It specializes in various formulation and drug delivery technologies, from conventional liposomes and PEGylated liposomes to polymer microspheres and nanoparticles for drug delivery. The company also provides contract research services for drug delivery formulation, formulation feasibility study, process development and scale-up, as well as analytical and non-clinical research services.
- December 15, 2025Science
Creative Diagnostics Launches New Line of Subcellular Fractions for In Vitro Metabolism Studies
Creative Diagnostics, a reagent supplier and developer focused on biologics quality control, has announced the expansion of its product portfolio with a comprehensive range of Subcellular Fractions for In Vitro Metabolism Studies, including products for hepatic, renal, intestinal, and skin metabolism. In vitro drug metabolism research has the advantage over in vivo studies of minimizing physiological interference, thereby enabling direct assessment of the selective metabolic action of enzymes on substrates. Due to their relatively simple preparation and stability, subcellular models are widely used in in vitro drug metabolism studies. Commonly used subcellular fractions include microsomes, S9 fractions, the cytoplasm, lysosomes, and mitochondria. Creative Diagnostics now offers a range of subcellular fractions to facilitate in vitro drug metabolism studies, including products for hepatic, renal, intestinal, and skin metabolism. For example, Creative Diagnostics can provide researchers with products for hepatic metabolism to support their specialized research. The liver is the primary organ for drug metabolism and biotransformation in the body, containing enzymes involved in Phase I and Phase II drug metabolism. Many in vitro metabolism models are based on hepatocyte-derived systems. Creative Diagnostics' liver metabolism-related products are from multiple animal species, including liver microsomes, liver S9 fractions, cytoplasm, lysosomes, and mitochondria. Creative Diagnostics also supplies renal metabolism products to support clients' specific research needs. The gastrointestinal wall plays a pivotal role in the first-pass metabolism of orally administered drugs, primarily through the action of CYP450 and UGT enzymes. However, esterase activity in the intestine can significantly affect drug metabolism. Therefore, when studying CYP450- and UGT-mediated metabolism, interference from esterase pathways must be minimized. Through continuous technological innovation, Creative Diagnostics has developed proprietary manufacturing processes that effectively preserve most CYP450 and UGT enzyme activity within intestinal subcellular fractions during preparation. The company now offers intestinal microsomes, intestinal S9 fractions, and cytoplasm from multiple animal sources to support intestinal drug metabolism research. In addition, Creative Diagnostics offers products related to intestinal metabolism for researchers. The kidney serves as a vital organ for Phase I and Phase II metabolic biotransformation beyond its physiological functions of maintaining water and electrolyte balance and excreting endogenous and exogenous substances. Creative Diagnostics provides renal microsomes, renal S9 fractions, and renal cytoplasmic products from various animal species to support research into renal drug metabolism. This innovative product line provides pharmaceutical companies and academic researchers with essential tools for in vitro metabolic studies and accelerates the drug discovery and development process. To learn more about the new Subcellular Fractions for In Vitro Metabolism Studies, or to find out more innovative solutions to accelerate research and development in the life sciences, please visit https://qbd.creative-diagnostics.com/products/subcellular-fractions-for-in-vitro-metabolism-studies.html . About Creative Diagnostics Creative Diagnostics is a global leader in the development and manufacturing of innovative tools and reagents for bioprocess impurity analysis. The company offers a comprehensive portfolio of solutions to support researchers in the quality control of biologics and provides biopharmaceutical quality, purity and safety assays, analytical methods and applications for the biotechnology and biopharmaceutical industries.
- December 15, 2025Health
Linda Kocieniewski, LCSW Expands EMDR Therapy Services for New York City Residents Seeking Deep, Accelerated Healing
Linda Kocieniewski, LCSW, a highly experienced New York City psychotherapist, is expanding her trauma-focused mental health services to better support individuals healing from anxiety, PTSD, and unresolved emotional distress. With a dedicated office in Midtown Manhattan, she now offers a full range of EMDR-based treatment options designed to meet the needs of busy professionals and trauma survivors seeking meaningful, long-term change. At the center of her practice is the availability of EMDR intensives , a structured therapeutic format that allows clients to work through challenges more efficiently than traditional weekly sessions. These intensives are especially helpful for individuals seeking deeper breakthroughs within a shorter timeframe. Kocieniewski also provides comprehensive EMDR therapy , an evidence-based approach known for its effectiveness in helping clients process traumatic memories, reduce emotional reactivity, and build greater internal resilience. The method is widely recognized for addressing issues such as anxiety, chronic stress, and past relational wounds. With years of clinical experience supporting diverse populations across the city, Kocieniewski continues to expand her focus on EMDR therapy New York , meeting the growing local demand for trauma-informed care delivered in a safe, professional environment. “Many people carry emotional burdens for years because they haven’t had access to the right tools,” said Linda Kocieniewski, LCSW. “My goal is to provide a supportive and efficient path toward healing so clients can move forward with confidence and clarity.” Her practice offers both in-person sessions at her New York office and secure online therapy for clients throughout the state, ensuring accessible trauma treatment options that fit busy schedules.
- December 15, 2025Health
Live Mindfully Psychotherapy Expands Trauma-Informed Mental Health Services in Houston, TX
Live Mindfully Psychotherapy, a leading Houston-based mental health practice, is expanding its trauma-informed services to meet the growing need for specialized and evidence-based care in the area. Under the direction of licensed therapist Kelsey Fyffe, the practice is deepening its focus on approaches that support individuals navigating anxiety, trauma, and complex emotional challenges. A key offering from the practice is EMDR therapy , an internationally recognized method that helps clients process trauma, reduce emotional distress, and move toward long-term healing. This modality continues to gain traction nationwide for its effectiveness in addressing unresolved memories and trauma responses. For clients seeking accelerated progress, Live Mindfully Psychotherapy also provides EMDR intensives , a structured treatment format designed for deeper therapeutic work in a condensed period. These intensives are especially beneficial for high-functioning professionals, trauma survivors, and individuals who prefer focused sessions over weekly appointments. In addition to trauma-focused care, the practice offers compassionate eating disorder therapy grounded in a holistic and supportive approach. Clients struggling with disordered eating patterns, body image concerns, or emotional relationships with food can access individualized treatment that prioritizes safety, empowerment, and long-term recovery. “At Live Mindfully Psychotherapy, we help clients reconnect with themselves and build lives grounded in balance and emotional clarity,” said Kelsey Fyffe. “Our goal is to create a space where healing is not only possible, but fully supported at every step.” The practice serves clients throughout Houston and accepts both in-person and virtual appointments, ensuring accessible care for residents across the region.
ALL NEWS
- Bin Li Contributes New Data-Driven Model Integrating BOM and ECBOM for Manufacturing Energy Analysis
- La Casetta delle Marche Transforms Into Italy's Leading Family Destination
- Carrie’s Pilates Franchise Division Celebrates The Grand Opening Of Its 6th Location In Las Colinas, Texas
- New Industry Insights Reveal Feedback Chaos as the Hidden Bottleneck in Product Development
- Meet the New Benchmark in Global Automotive Safety, GEELY OPENS WORLDS LARGEST VEHICLE TESTING CENTRE
- American Twins Cash & Roman Felber Target British F4 Success with Fortec Motorsport
- New Market Report Reveals Key Trends, Multiples, and Strategic Insights in Manufacturing & Industrials M&A
- RecyGlo and Wongpanit Partners with ERTH Ventures To Build Thailand’s First Integrated MRV To Digital Carbon Credits At National Scale
- Zeca Media Releases Report On How AI Tools Are Changing Customer Search Behavior
- iDenfy was recognized as a top ID verification platform at the global FF Awards 2025
- HackerNoon and GPTZero Announce Partnership to Expand AI Transparency in Tech Publishing
- CD Bioparticles Launches Comprehensive Animal mRNA Vaccine Solutions to Support Veterinary Research
- Creative Diagnostics Launches New Line of Subcellular Fractions for In Vitro Metabolism Studies
- Linda Kocieniewski, LCSW Expands EMDR Therapy Services for New York City Residents Seeking Deep, Accelerated Healing
- Live Mindfully Psychotherapy Expands Trauma-Informed Mental Health Services in Houston, TX
- Mindful Mental Health Counseling Expands Holistic Support for Individuals Seeking Therapy in New York City
- NK Psychological Services Strengthens Access to Compassionate Therapy Support for Individuals and Families in Chicago, IL
- Los Angeles Therapist Expands Access to Trauma-Informed Care for Adults Seeking Healing and Emotional Growth
COMMUNICATE. COMMAND. COMMERCE.
Lead the conversation of your brand & win more customers with MarketersMEDIA Solutions.
Explore Now
Google
RSS