-- Creative Bioarray, one of the leading providers of cutting-edge biological research solutions, is dedicated to helping accelerate research and drug development. Creative Bioarray keeps providing essential products and services to empower pharmaceutical, biotech, government, and academic teams to turn possibilities into breakthroughs. Recently, it announced the introduction of its flagship High-Fat Diet-Induced Obesity (DIO) Model, designed to meet the pressing needs of researchers addressing the global obesity epidemic.
With over 650 million adults worldwide classified as obese, obesity has become a significant public health crisis associated with various metabolic disorders, including type 2 diabetes and cardiovascular diseases. Projections suggest that by 203, one in five women and one in seven men will be affected by obesity, and the global obesity therapeutics market is expected to surpass $100 billion, underscoring the need for effective research tools.
Creative Bioarray offers well-qualified diet-induced obesity models for metabolic research, providing a comprehensive assessment of therapies designed to treat obesity and its comorbidities. Its expert scientists specialize in gold standards of care and offer the following diet-induced obesity models and metabolic syndrome studies:
- DIO mouse model (Diet-induced obesity model in C57BL/6 mice)
- Zucker Fatty Rat Model
- Diabetic Complication Model
- In vitro obesity and metabolic syndrome cell models
Customizable model development is also available to assess PK/PD relationships and target engagement. All metabolic syndrome studies are supported by biomarker analysis, immunology, pharmacokinetics, and pathology services. In vivo IVIS imaging is available to follow cell and gene therapies.
“To further support your cardiovascular and metabolic research, we offer MASH models, Type 1 and Type 2 diabetes services, glucose tolerance testing, and dyslipidemia and atherosclerosis models,” said Hannah Cole, the marketing director of Creative Bioarray.
Creative Bioarray’s DIO Model utilizes the C57BL/6J mouse strain, renowned for its susceptibility to diet-induced obesity. By administering a high-fat diet (HFD) consisting of 45-60% kcal from fat, this model induces progressive weight gain, insulin resistance, dyslipidemia, and hepatic steatosis, closely mimicking the conditions associated with human obesity.
“Our High-Fat Diet-Induced Obesity Model is a game-changer for researchers striving to combat obesity and its related health issues,” said Hannah Cole. “This model not only delivers a standardized research platform but also offers comprehensive scientific support to enable our customers to generate robust and meaningful results in their studies.”
The DIO Model features an array of endpoints for robust metabolic characterization, including body composition, liver function assessments, and evaluations of inflammatory markers. Researchers can customize the model protocol to align with specific study needs, fostering flexibility and efficacy in their investigations.
Moreover, the DIO Model addresses crucial research gaps regarding the progression from steatosis to fibrosis, a critical component of metabolic disease that has been challenging to investigate. Creative Bioarray aims to bridge these gaps by providing a reliable research environment that minimizes phenotypic drift.
“The significance of our High-Fat Diet-Induced Obesity Model in metabolic research cannot be overstated,” added Cole. “By equipping researchers with reliable tools to study obesity and its comorbidities, we aspire to accelerate the development of innovative solutions that can profoundly impact patient care.”
About Creative Bioarray
Creative Bioarray’s products and services support clients from basic research and safety assessment to global manufacturing. For more information on Creative Bioarray’s High-Fat Diet-Induced Obesity Model and how it can enhance your research efforts, please visit Creative Bioarray’s website. Furthrmore, we provide the solutions you need to bring new therapies to patients faster from discovery to early development and safe manufacturing.
Contact Info:
Name: Hannah Cole
Email: Send Email
Organization: Creative Bioarray
Address: Shirley, NY 11967, USA
Phone: 16313868241
Website: https://www.creative-bioarray.com/
Release ID: 89196310
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