With years of experience in the field of phage display and antibody engineering, Creative Biolabs is glad to be the first company in the biotech market that brings out classical guinea pig immunization and novel monoclonal guinea pig antibody production service based on its advanced — phage display platform.
Guinea pig does not exist naturally in the wild. It has been used in experiments for centuries and is regarded as one of the earliest used laboratory animals. Just as other rodents, guinea pigs have remarkable biological similarities to humans. Because of this feature, they are quite useful in various research areas, including infectious disease studies of tuberculosis and diphtheria as well as the antibody development in response to extreme allergic reactions or anaphylaxis.
Guinea pigs are more sensitivity compared with other rodents, providing a crucial feature in human disease study. What’s more, the difference of genotype enables guinea pig to generate stronger antibody response to some antigens that are highly homologic with humans, mouse and rats. For example, guinea pig insulin has 18 residues differ from human insulin while there are only 4 residues difference between rat and mice insulin and human insulin, enabling guinea pigs to generate high affinity anti-insulin antibodies. Therefore, the production of monoclonal guinea pig antibody may offer novel solutions for some specific targets.
Hybridoma cell immunization is commonly used in traditional guinea pig antibody production. However, Creative Biolabs developes novel monoclonal guinea pig antibodies through its well-recognized phage display technology.
“After routine immunization strategy, our scientists are able to generate high diversity phage display guinea pig antibody libraries and isolate high specific and affinity monoclonal guinea pig antibodies using our biopanning techniques,” said Dr. Monika, scientific officer of Creative Biolabs, “As alternatives, we also provide Native™ Guinea Pig Antibody Discovery Service, which is based on antigen-specific B lymphocytes cytometry technology and Guinea Pig hybridoma development service.”
About Creative Biolabs
Creative Biolabs is one of the well-recognized providers for high quality monoclonal antibodies. Over the past decade, its scientists have been committed to offering the most comprehensive monoclonal antibodies from various species, which currently involves guinea pig, shark, rabbit, chicken, llama, camel, dog, mouse, rat, human and so on.
Name: Candy Swift
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Organization: Creative Biolabs
Address: 45-1 Ramsey Road
Release ID: 133907