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Cell expansion technology has been emerging as a promising therapeutic solution for many diseases and is used for engineering, replacing, or regenerating human tissues, cells, and organs to restore normal function. Products of cell expansion market are segmented into instruments and consumables. The instruments are segmented into cell expansion supporting instruments, bioreactors and automatic cell expansion systems. Cell expansion supporting equipments include flow cytometer, centrifuge, cell counters and others. Bioreactors are segmented into stirred type bioreactors, microcarrier-based anchorage-dependent stirred type bioreactors, suspension-based anchorage independent stirred type bioreactors, hollow fibre/perfusion bioreactors, bubble column and airlift bioreactor, single/disposable use bioreactor and others. Consumables are segmented into reagents, media, sera and disposables. Disposables are further sub-segmented into culture vessels, bioreactor accessories and others.By cell types, the cell expansion markets are divided into animal cells, human cells, bacterial cells and others. The human cell includes adult stem cells, induced pluripotent stem cells and embryonic stem cells. Adult stem cells are segmented into mesenchymal stem cells, hematopoietic stem cells and neural stem cells. Others include yeast cells and insect cells.
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By application, the cell expansion markets are divided into regenerative medicine and stem cell research, cancer studies and others. The end users of the cell expansion market are segmented into academics and research institutes, biotechnology and biopharmaceutical companies, hospital, biobanks and others.
Among the cell expansion products, the consumables dominated the market by occupying a largest share and instruments market is estimated to be the fastest growing segment from 2015 to 2022. In cell types, human cell types is the largest segment as well as the fastest growing segment. In applications, the regenerative medicine and stem cell research is the largest segment and is the fastest growing segment with a highest CAGR of 18.1% from 2015-2022. By end- users, hospitals and bio banks are the largest segment with a share of 37.0% and also, the fastest segment from 2015 to 2022.
Geographically, North America is the largest market followed by Europe and Asia. The APAC region is the fastest growing region with a CAGR of 20.8% from 2015 to 2022 suggesting an array of opportunities for growth and likely to be getting into the eyes of new investors in the cell expansion market. Growth in the Asian market is attributed to rising prevalence of chronic diseases and increased government initiatives for stem cell research.
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The cell expansion market is expected to grow at a double digit CAGR to reach $23,997 million by 2022. Rising prevalence of chronic diseases, increasing government funding for research, increased investments in cell based products, growing number of GMP-certified production facilities and 3D cell expansion technology are some of the drivers in the cell expansion global market. High cost of cell-based research, use of unregulated products, quality issues for end users, ethical concerns regarding research on cell biology and stringent regulation are some of the factors hampering the market.
The cell expansion global market is a highly competitive market and all the existing players in this market are involved in developing new and advanced products to maintain their market shares.
Some of the key players of the cell expansion market are Becton Dickinson and Company (U.S.), Corning, Inc. (U.S.), Danaher Corporation (U.S.), Eppendorf AG (Germany), GE Healthcare (U.K), Lonza Group Ltd. (Switzerland), Merck KGAA (Germany.), Miltenyi Biotec (Germany), STEMCELL Technologies (Canada), Terumo Corporation (Japan) and ThermoFisher Scientific Inc. (U.S.).
The report provides an in depth market analysis of the above mentioned segments across the following regions:
• North America
• Europe
• Asia-Pacific
• Rest of the World (RoW)
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Major Points Contained in Table of content
1 EXECUTIVE SUMMARY 20
2 INTRODUCTION 28
2.1 KEY TAKE AWAYS 28
2.2 REPORT DESCRIPTION 28
2.3 MARKETS COVERED 30
2.4 STAKEHOLDERS 32
2.5 RESEARCH METHODOLOGY 32
2.5.1 MARKET SIZE ESTIMATION 34
2.5.2 MARKET CRACKDOWN AND DATA TRIANGULATION 36
2.5.3 SECONDARY SOURCES 37
2.5.4 PRIMARY SOURCES 38
2.5.5 KEY DATA POINTS FROM SECONDARY SOURCES 38
2.5.6 KEY DATA POINTS FROM PRIMARY SOURCES 39
2.5.7 ASSUMPTIONS 39
3 MARKET ANALYSIS 41
3.1 INTRODUCTION 41
3.2 MARKET SEGMENTATION 42
3.3 FACTORS INFLUENCING MARKET 44
3.3.1 DRIVERS AND OPPORTUNITIES 44
3.3.1.1 Rising Prevalence of Chronic Diseases 44
3.3.1.2 Increasing Government Funding for Research 45
3.3.1.3 Increased Investments in Cell Based Research 47
3.3.1.4 Growing Number of GMP-Certified Production Facilities. 48
3.3.1.5 3D Cell Expansion Technology 49
3.3.1.6 Countries in Asia-Pacific Region to Present High-Growth Opportunities 51
3.3.2 RESTRAINTS AND THREATS 52
3.3.2.1 High Cost of Cell-Based Products 52
3.3.2.2 Use of Unregulated Products 52
3.3.2.3 Quality Issues for End Users 53
3.3.2.4 Ethical Concerns Regarding Research on Cell Biology 54
3.3.2.5 Stringent Regulation 55
3.4 PORTER’S FIVE FORCE ANALYSIS 55
3.4.1 THREAT OF NEW ENTRANTS 55
3.4.2 THREAT OF SUBSTITUTES 56
3.4.3 BARGAINING POWER OF SUPPLIERS 58
3.4.4 BARGAINING POWER OF BUYERS 59
3.4.5 COMPETITIVE RIVALRY 59
3.5 REGULATORY GUIDELINES 60
3.5.1 U.S. 60
3.5.2 EUROPE 61
3.5.3 INDIA 62
3.5.4 CHINA 63
3.5.5 JAPAN 64
3.6 UPCOMING TECHNOLOGIES 65
3.7 SUPPLY CHAIN ANALYSIS 68
3.8 MARKET SHARE ANALYSIS BY MAJOR PLAYERS 71
3.8.1 CELL EXPANSION GLOBAL MARKET SHARE ANALYSIS,
BY KEY PLAYERS, 2015 71
3.8.2 SINGLE-USE BIOREACTOR MARKET REVENUE,
BY MAJOR PLAYERS, 2015 74
3.9 PATENT TRENDS 76
4 CELL EXPANSION GLOBAL MARKET, BY PRODUCTS 79
4.1 INTRODUCTION 79
4.2 INSTRUMENTS 81
4.2.1 CELL EXPANSION SUPPORTING EQUIPMENTS 84
4.2.1.1 Flow Cytometers 87
4.2.1.2 Centrifuge 90
4.2.1.3 Cell Counters 92
4.2.1.4 Other Cell Expansion Supporting Equipments 94
4.2.2 BIOREACTORS 97
4.2.2.1 Stirred Type Bioreactors 101
4.2.2.2 Microcarrier-Based Anchorage-Dependent Stirred Type Bioreactors 103
4.2.2.3 Suspension-Based Anchorage Independent Stirred Type Bioreactors 107
4.2.2.4 Hollow Fiber/Perfusion Bioreactors 108
4.2.2.5 Bubble Column And Airlift Bioreactors 111
4.2.2.6 Single Use/Disposabable Bioreactors 112
4.2.2.7 Other Bioreactors 115
4.2.3 AUTOMATED CELL EXPANSION SYSTEMS 117
4.3 CONSUMABLES 119
4.3.1 REAGENTS, MEDIA AND SERA 122
4.3.2 DISPOSABLES 125
4.3.2.1 Culture Vessels 128
4.3.2.2 Bioreactor Accessories 131
4.3.2.3 Others 132
5 CELL EXPANSION MARKET, BY TYPES 135
5.1 INTRODUCTION 135
5.2 ANIMAL CELL 137
5.3 HUMAN CELL 144
5.3.1 ADULT STEM CELL 148
5.3.1.1 Neural Stem Cells (NSCs) 152
5.3.1.2 Hematopoietic Stem Cells (HSCs) 154
5.3.1.3 Mesenchymal Stem Cells (MSC) 156
5.3.2 INDUCED PLURIPOTENT STEM CELL (IPSC) 161
5.3.3 EMBRYONIC STEM CELL 163
5.4 BACTERIAL CELLS 165
5.5 OTHERS 167
6 CELL EXPANSION GLOBAL MARKET, BY APPLICATIONS 171
6.1 INTRODUCTION 171
6.2 REGENERATIVE MEDICINE AND STEM CELL RESEARCH 173
6.3 CANCER STUDIES 177
6.4 OTHERS 180
7 CELL EXPANSION GLOBAL MARKET, BY END USERS 185
7.1 INTRODUCTION 185
7.2 ACADEMIC AND RESEARCH INSTITUTES 187
7.3 BIOTECHNOLOGY AND BIOPHARMACEUTICAL COMPANY 189
7.4 HOSPITALS AND BIO BANKS 191
7.5 OTHERS 193
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