-- Because of the diverse functions and wide use of nucleic acids, it is essential to develop fast and effective methods to detect nucleic acids from complex media. Amerigo Scientific launches its isothermal amplification instrument range to overcome the limitations of current nucleic acid amplification technologies.
The detection and amplification of nucleic acids are core processes in life-science research and related analytical applications. For many years, the polymerase chain reaction (PCR) has been the most commonly employed method to amplify and identify minute amounts of nucleic acids. However, PCR requires bulky and costly temperature cycling instruments, which limit the applications of PCR in field research or resource-limited laboratories. In contrast, isothermal nucleic acid amplification technology has emerged as a promising alternative, enabling rapid and efficient amplification of target nucleic acids at a constant temperature without the need for thermal cycling.
Amerigo Scientific's isothermal amplification instruments leverage the unique advantages of isothermal nucleic acid amplification technology, including its isothermal operation, simplicity, cost-effectiveness, robustness, high sensitivity, strong specificity, and excellent amplification efficiency. Unlike PCR, these instruments eliminate the need for thermocyclers, and their amplification products can be monitored in real time through turbidity measurement or visual color change inspection, removing the requirement for gel electrophoresis. The Isothermal amplification technology's low energy consumption and structural simplicity also allow it to be integrated into compact systems, expanding its usability in portable and on-site detection scenarios.
The isothermal amplification technologies supported by these instruments cover a wide range of mechanisms, such as transcription mediated amplification (TMA)/self-sustained sequence replication (3SR), nucleic acid sequence-based amplification (NASBA), signal-mediated amplification of RNA technology (SMART), and circular helicase-dependent amplification (cHDA). Each technology varies in parameters like primer and enzyme quantity, amplification temperature, template type, sample volume requirement, and detection method, enabling researchers to select the most suitable option based on their specific research objectives. Beyond nucleic acid detection, the technology has been extended to target a broad spectrum of substances including proteins, cells, small molecules, and ions, and its combination with nanotechnology has opened up new prospects in biosensing, bioimaging, and nanomedicines, providing abundant nucleic acid materials for fabricating high-order nucleic acid nanostructures, nucleic acid template-metal nanostructures, and nucleic acid hydrogels.
The launch of these isothermal amplification instruments complements Amerigo Scientific's comprehensive laboratory equipment offering. Amerigo Scientific provides a full range of high-quality, durable lab tools, covering general equipment (such as freezers, incubators, shakers, analytical balances, and pipettes) and specialized equipment (including autoclaves, cell culture systems, PCR machines, mass spectrometers, and flow cytometers). This one-stop supply capability enables Amerigo Scientific to meet the high-standard requirements of laboratories for diverse research and analysis tasks.
About Us: About Amerigo Scientific Amerigo Scientific, as a recognized distributor in the United States, collaborates closely with leading manufacturers worldwide and invites cooperation from all companies and institutions in the area of reagents, kits, antibodies, and many other products for life science, biochemistry, and biotechnology. Its professional team is equipped with excellent technical support and thoughtful customer service. As most of its employees have earned a graduate (Ph.D. or M.S.) degree in life science, they can comprehend customers’ questions or concerns and are always ready to provide individualized customer service of high standards.
Contact Info:
Name: Phoebe Davis
Email: Send Email
Organization: Amerigo Scientific
Website: https://www.amerigoscientific.com/
Release ID: 89179755
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