-- Creative Peptides has newly released its custom service for accelerating further life sciences research. Progresses in understanding the molecular pathogenesis of human malignancies could vary for certain assistance, but the Cell-penetrating Peptides Synthesis Service has developed to be a leading one.
As is known, cell-penetrating peptides are highly cationic and usually rich in arginine and lysine amino acids. They have the exceptional property of carrying into the cells a wide variety of covalently and noncovalently conjugated cargoes such as proteins, oligonucleotides and even 200 nm liposomes. Therefore they are extremely attractive candidates to transport drugs to the interior of cells.
Current view in cellular biology has indicated a fact that the cellular internalization of hydrophilic macromolecules can only be achieved through the classical endocytosis pathway. Thus, gaining more attention on cell-penetrating peptides could be significant in modern peptides research. Typically, CPPs are often passive and nonselective yet must be functionalized or chemically modified to create effective delivery vectors that succeed in targeting specific cells or tissues.
In addition, effective medical systemic delivery systems should require attention to details in both design of the delivered cargo and cell-penetrating peptides used to deliver it. To be more specific, such cellular delivery using cell-penetrating peptides shows some advantages over conventional techniques because they’re efficient for a variety of cell types, which might have a potential therapeutic application.
To stand out the importance of cell-penetrating peptides, Creative Peptides has taken cellular penetration of potential drugs into mammalian cells as one of the general upgrade mission. Applications of cell-penetrating peptides for delivering various macromolecules with biological functions into cells begin to come into vogue.
In fact, many novel CPPs have already been used to effectively transfect a variety of cell types to elicit specific biological responses. Creative Peptides, equipped with experienced tech panel, is able to help solve the challenges in peptide synthesis progress. As an international supplier of innovative peptide synthsis services for the academic and industrial community, Creative Peptides has committed to a comprehensive series of Cell-penetrating Peptides Synthesis Services and Total Quality Management (TQM) to fulfill customers' complete satisfaction, with the state-of-the-art equipment.
Creative Peptides offers excellent Cell-penetrating peptides that:
• Are able to rapidly translocate large molecules into many cell lines including both adherent and suspension cells
• Have low toxicity for live cells
• Are targeted to different cell lines thereby achieving high yield of delivery efficiency
• Minimize decomposition product due to complete post-internalizational break down of CPPs
• Are suitable for in vitro and in vivo experiments
• Contain selected helper reagents for fine-tuning of experimental set ups
• Are safe to use without any special precautions
• Linear peptides conjugated to proteins or oligonucleotides.
Typical delivery specifications include:
• HPLC chromatogram
• Mass spec analysis
• Synthesis report
• Certificate of analyses
CPPs has been seen as an attractive pharmaceutical and biochemical tool because they can be used for the intracellular uptake and delivery of various macromolecules. For more information, please visit the site for details.
About Author:
Creative Peptides is specialized in the process development and the manufacturing of bioactive peptides. It provides customers with manufacturing services to the peptide manufacturers for the biopharmaceutical market. The goal of Creative Peptides is to offer a high-quality service for all the peptide development and manufacturing needs.
Contact Info:
Name: Caroline Miller
Email: Send Email
Organization: Creative Peptides
Address: 45-16 Ramsey Road, Shirley, NY 11967, USA
Phone: 5166698109
Website: http://www.creative-peptides.com/
Release ID: 122373
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